Adenomatoid odontogenic tumor (AOT), a benign (hamartomatous) lesion of odontogenic origin, is an uncommon tumor which affects mainly. Adenomatoid odontogenic tumor (AOT) is a rare odontogenic tumor which is often misdiagnosed as odontogenic cyst. To acquire additional. Adenomatoid odontogenic tumor is a hamartomous benign neoplasia of odontogenic origin. It appears mostly in young patients and females, the maxillary.

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Adenomatoid odontogenic tumor arising from a dentigerous cyst – A case report. AOT affects young individuals with a female predominance, occurs mainly in the second decade, and usually surrounds the crown of unerupted teeth. adenomayoid

Well-circumscribed adenomatid lesion same in right maxilla with impacted teeth 13 and 14, with well-defined radio-opaque border. International histological classification of tumours: Case report and review of literature.

The large adenomatoid structures, resulting from the circular tridimensional, “tubular” configuration of the columnar cells and cylindrical superficial cells of the REE due to its hamartomatous growth, would be formed in recent tumors, right from their onset.

Few cases of AOT, like this case, were humor in the literature in association with a maxillary lateral incisor.

Adenomatoid odontogenic tumor, an uncommon tumor

The extraction of the tooth 23 was done in Aprilwith surgery to bond a bracket on tooth 22, but it failed due to lack of the localization and the consistency of the tissues around the impacted tooth. Adenomatoid odontogenic tumor arising from dentigerous cyst: Cells forming the adenomatoid structures and the solid areas were not positive in two of the samples and varied in the others Figure 1. In the past, various names have been used for zdenomatoid similar to AOT in the literature.

From the moment at which the cells no longer have their secretory function, CK14 is expressed again. It is usually associated with an impacted canine.

Study on the origin and nature of the adenomatoid odontogenic tumor by immunohistochemistry

J Oral Maxillofac Surg ; Mineralized structures resembling Liesegang rings, dystrophic calcification areas, and other small intercellular eosinophilic hyaline deposition, with shapeless light or dark pinkish appearance, sometimes lamellar and concentric were present.


We believe that AOT cells might be able to secrete two types of substances, according to their functional capability: Follow-up 12—24 months after surgery was performed, and no recurrence was noted. The surgical specimen may be solid or cystic. AOTs are benign and present a very low recurrence, making it unnecessary to carry out extensive and aggressive surgery [ 23 ]. Case Report A year-old female child reported to our clinic with a complaint of missing teeth in the right maxilla with a medical history taking epileptic drugs.

Aspiration of the smelling yielded 2 ml of straw color fluid mixed with blood. However, in exceptional cases of large tumors or risk of bone fracture, partial resection, in a block of the mandible or maxilla, has been indicated.

This article has been cited by. PCNA specifically labelled the spindled areas and peripheral cords of the AOT, indicating that these areas are responsible for tumor growth. This finding might resemble the basal lamina next to the internal and external epithelium of the enamel organ, or the surface of the reduced enamel epithelium in the enamel maturation stage.

The specific PCNA cell labelling in the AOTs, not present in the flat and stellate cells among the spindled areas, helped to rule out a neoplastic nature for the tumor.

A retrospective study of cases in a Chinese population.

Case report and review of the literature. View at Google Odontogemic A. Support Center Support Center. Interestingly, our present cases had some unusual clinical and radiographic features that distinguished it from most normal types of AOT. Philipsen HP, Birn H. Eur J Oral Sciv. Odontogeniic more than one tooth may also be related with AOT as noticed in our case analysis wherein permanent incisors, canines, and premolars were involved with the lesion. Int J Oral Surg. The tumor was well encapsulated, and the lateral incisor was easily removed with the lesion Figure 4.

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Two thirds of the cases are associated with an impacted tooth usually being the canine. There are flakes of radio-opaque areas inside the lesion.

Hematoxylin-eosin stained sections were made for routine histological examination. As far as the extrafollicular variant, we agree with Philipsen, et al.

Case Reports in Dentistry

Orthopantomogram after 2 months of stage one surgery showing regression of the lesion Click here to view. Usually, they do not exceed cm in diameter. Bull Tokyo Dent Coll. The consistency is firm and fluctuation of the cortex in one area is present. Services on Demand Journal. This stage is called “protective stage of amelogenesis”, which avoids cementoblastic differentiation in the follicle and cementum deposition or “osteodentin” next to the enamel Ten Cate 23 So, the variation in the expression of CK14 indicated variable differentiations of the tumoral cells.

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Int J Oral Health Sci ;4: The adenomatoid odontogenic tumor is mostly limited to younger patients between 10 and 30 adenomatid [ 367 ], and two-thirds of all cases are diagnosed when the patient is 10—19 years old.

Idontogenic studies in the literature have used the immunohistochemistry technique to analyze AOTs. It is a tumor lined by odontogenic epithelium in a variety of histoarchitectural patterns, which are embedded in a mature connective tissue stroma. An enucleation was done.

Post operative facial view Click here to view. The tumor is composed of spindle-shaped or polygonal cells forming sheets and whorled masses in a scant connective tissue stroma. Int J Oral Maxillofac Pathol. Tables 2 and 3 summarize the immunohistochemical results obtained using paraffin sections of formalin fixed tissue.