Buy Alloxan monohydrate (CAS ), a water soluble pyrimidine derivative & glucose analog. Join researchers using high quality Alloxan monohydrate. Alloxan monohydrate | C4H4N2O5 | CID – structure, chemical names, physical and chemical properties, classification, patents, literature, biological. Alloxan monohydrate (Sigma Aldrich, St. Louis, MO, USA; stored at 4°C) was dissolved in normal saline at room temperature and was injected by intraperitoneal.

Author: Nikinos Dailmaran
Country: South Africa
Language: English (Spanish)
Genre: Health and Food
Published (Last): 13 February 2008
Pages: 145
PDF File Size: 10.26 Mb
ePub File Size: 15.82 Mb
ISBN: 883-4-34618-509-8
Downloads: 79318
Price: Free* [*Free Regsitration Required]
Uploader: Zulusar

Because it selectively kills the insulin -producing beta-cells found in the pancreas, alloxan is used to induce diabetes in laboratory animals.

Alloxan monohydrate | CAS | SCBT – Santa Cruz Biotechnology

Our Cookie Policy explains how you can opt-out of the cookies we use. Your account has been deactivated.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3. However, we experienced an inconsistent alolxan unpredictable response with alloxan, similar to that discussed by Jain et al. The alloxan model of diabetes was first described in rabbits by Alloxxan, Sheehan and McLetchie in Email address already exists, please enter a new valid email address. It is classified as a derivative of pyrimidine.

PubMed used the cytotoxic compound Alloxan monohydrate to induce diabetes in Swiss albino mice.


Journal List Indian J Pharmacol v. Effect of rate of injection of alloxan on development of diabetes in rabbits. Why create an account?

Alloxan monohydrate Sigma Aldrich, St. The Institutional Animal Ethics Committee approved the experimental protocol.

Brugnatelli called it ossieritrico erythric acid [p. Murexide is the product of the complex in-situ multistep reaction of alloxantin and gaseous ammonia. We, therefore, agree with the viewpoint of Jain DK et al. Antidepressant-like effects of Brassica juncea L. In the chapter “Nitrogen” of his memoir The Periodic TablePrimo Levi tells of his futile attempt monohydrste make alloxan for a cosmetics manufacturer who has read that it can cause permanent reddening of the lips.


These are some of the earliest known organic compounds. Hypoglycemic effects of vanadium on alloxan monohydrate induced diabetic dogs.

Induces oxidative allooxan damage to nuclear and mtDNA.

Alloxan was used in the production of the purple dye murexidediscovered by Carl Wilhelm Scheele in Please visit our frequently asked questions FAQ page for more details. These results indicate that the susceptibility to diabetogenic and toxic effects of alloxan differs mohohydrate animals of the same species.

Please let us know so that we can cite the reference in this datasheet.

Call us Toll Free at Click on image or enlarge button to enlarge. I recommend this reagent Date published: Alloxan is also used in research models to induce diabetes. Get resources and offers direct to your inbox Sign up. General and Comparative Endocrinology.


Alloxan: An unpredictable drug for diabetes induction?

Sign Up for Santa Cruz Biotechnology news and announcements. Submit a review Submit a question.

A monohyrate compound that causes oxidative base damage to nuclear DNA. All trademarks are the property of their respective owners. There are currently no Customer reviews or Questions for ab It was originally obtained by oxidation of uric acid by nitric acid. Schocken,translated by Raymond Rosenthal, Santa Cruz Biotechnology, Inc. Author information Copyright and License information Disclaimer. Anomalies in alloxan-induced diabetic model: Variations of susceptibility to alloxan induced diabetes in the rabbit.

Your browser does not have JavaScript enabled and some parts of this website will not work without it. Please contact our Customer Care Department to inquire about current availability jonohydrate this chemical, and an estimated shipping and delivery time to the Phillippines.